Gwenom, Remorseless leads a life payment strategy where attacking lets you cheat spells off the top of your library by spending life instead of mana, fueling a relentless drain engine built around cards that cause opponents to lose life whenever you gain life, most notably Marauding Blight-Priest and Defiling Daemogoth. The deck accumulates life through lifelink creatures, life-gaining enchantments and artifacts, and drain effects like Exsanguinate, then converts that life total into a resource for both casting spells and pressuring opponents simultaneously. Font of Agonies turns the constant life payments from Gwenom's ability into repeatable creature removal, while Gray Merchant of Asphodel and Syr Konrad, the Grim provide additional paths to draining opponents out through devotion and graveyard activity respectively.

Lady Venom decklist

• Gray Merchant of Asphodel
• Death Cultist
• Vampire Nighthawk
• Font of Agonies
• Creeping Chill
• Gonti's Machinations
• Evolving Wilds
• Blood Tithe
• Trespasser's Curse
• Everflowing Chalice
• Demon's Horn
• Mortuary
• Dark Ritual
• Tendrils of Corruption
• Staff of the Death Magus
• Tragic Slip
• Prism Ring
• Murder
• Temple of the False God
• Sadistic Sacrament
• Blood Pet
• Terramorphic Expanse
• Tendrils of Agony
• Professor Onyx
• Feign Death
• Unhallowed Phalanx
• Charcoal Diamond
• Chain of Smog
• Marauding Blight-Priest
• Crypt Incursion
• Nighthawk Scavenger
• Join the Dead
• Lavaspur Boots
• Consuming Corruption
• Stargaze
• Sinister Monolith
• Savor
• Wishclaw Talisman
• Cling to Dust
• Diamond Mare
• Stab
• Chalice of Life // Chalice of Death
• Dauthi Voidwalker
• Noxious Gearhulk
• Syr Konrad, the Grim
• Sepulchral Primordial
• Arcane Signet
• Sol Ring
• Myriad Landscape
• The Endstone
• Thriving Moor
• Path of Ancestry
• Auntie's Sentence
• Dream Beavers
• Squirrelanoids
• Defiling Daemogoth
• Umbral Collar Zealot
• Veinwitch Coven
• Petrified Hamlet
• Feed the Swarm
• Dark Deed
• Cruel Alliance
• Hobbit Hole
• Well-Worn Spatula
• Ravening Warg
• Dreaded Bat-Cloud
• Stir Up Trouble
• Exsanguinate
• Archon of Cruelty
• 27× Swamp
• Season of Loss
• Baron Helmut Zemo
• Pox Plague